Search on: PIAS1 PROTEIN INHIBITOR OF ACTIVATED STAT 
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Descriptor English:   Protein Inhibitors of Activated STAT 
Descriptor Spanish:   Proteínas Inhibidoras de STAT Activados 
Descriptor Portuguese:   Proteínas Inibidoras de STAT Ativados 
Synonyms English:   PIAS Proteins
PIAS1 Protein
PIAS1 Protein Inhibitor of Activated STAT
PIAS2 Protein Inhibitor of Activated STAT
PIAS3 Protein Inhibitor of Activated STAT
PIAS4 Protein Inhibitor of Activated STAT  
Tree Number:   D12.644.360.024.319
D12.776.157.057.124
D12.776.476.024.402
Definition English:   A family of structurally related proteins that are constitutively expressed and that negatively regulate cytokine-mediated SIGNAL TRANSDUCTION PATHWAYS. PIAS proteins inhibit the activity of signal transducers and activators of transcription. 
History Note English:   2006(1998) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   50781 
Unique Identifier:   D050828 

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